Package: MetaHD
Type: Package
Title: A Multivariate Meta-Analysis Model for High-Dimensional Data
Version: 0.1.6
Authors@R: c(
  person("Jayamini", "Liyanage", role = c("aut", "cre"),
         email = "j.liyanage@latrobe.edu.au"),
  person("Alysha", "De Livera", role = "aut",
         email = "a.delivera@latrobe.edu.au"),
  person("Luke", "Prendergast", role = "aut",
         email = "luke.prendergast@latrobe.edu.au"))
Maintainer: Jayamini Liyanage <j.liyanage@latrobe.edu.au>
Author: Jayamini Liyanage [aut, cre], Alysha De Livera [aut], Luke
        Prendergast [aut]
Description: Performs multivariate meta-analysis for high-dimensional
        data to integrate and collectively analyse individual-level
        data from multiple studies, as well as to combine summary
        estimates. This approach accounts for correlation between
        outcomes, incorporates within- and between-study variability,
        handles missing values, and uses shrinkage estimation to
        accommodate high dimensionality. The 'MetaHD' R package
        provides access to our multivariate meta-analysis approach,
        along with a comprehensive suite of existing meta-analysis
        methods, including fixed-effects and random-effects models,
        Fisher's method, Stouffer's method, the weighted Z method,
        Lancaster's method, the weighted Fisher's method, and
        vote-counting approach. Visualisation tools are provided for
        interpreting and comparing results across methods, including
        Venn diagrams, UpSet plots, and ROC curves, heatmaps of pooled
        effect sizes and correlations among outcomes. A detailed
        vignette with example datasets and code for data preparation
        and analysis is available at
        <https://alyshadelivera.github.io/MetaHD_vignette/>.
License: GPL-3
Encoding: UTF-8
Depends: R (>= 4.4.0)
LazyData: true
LazyDataCompression: xz
Imports: dplyr, tidyr, metafor, corpcor, nloptr, Matrix, matrixcalc,
        Rcpp (>= 1.0.0), dynamicTreeCut, cluster, future.apply,
        metapro, metap, UpSetR, pROC, graphics, grDevices, tools,
        ComplexHeatmap, circlize
LinkingTo: Rcpp, RcppArmadillo
Suggests: gVenn, testthat (>= 3.0.0)
biocViews:
Config/roxygen2/version: 8.0.0
NeedsCompilation: yes
Packaged: 2026-10-07 11:52:54 UTC; root
Config/pak/sysreqs: cmake libfftw3-dev libicu-dev libpng-dev perl
Repository: https://jayaminicl.r-universe.dev
Date/Publication: 2026-07-09 12:30:02 UTC
RemoteUrl: https://github.com/cran/MetaHD
RemoteRef: HEAD
RemoteSha: f49e086e282125d3128d68b8eb0f7e99c7144ea7